It's certainly possible to have an up and running 3DS site right now. That's, of course, assuming you haven't put much time and effort in supporting technologies that aren't standard for every browser (i.e Flash.) The real obstacle to making a 3DS website now is how the screen size differentiation will be handled.
It's my job to help the next generation, and set a good example for them. And for that I'll gladly lay down my life.
